Resident Population in Florence County, SC was 137.21400 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Florence County, SC reached a record high of 138.83700 in January of 2014 and a record low of 89.63600 in January of 1970. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Florence County, SC - last updated from the United States Federal Reserve on June of 2024.