Roanoke City, VA - Population Estimate, Total, Hispanic or Latino (5-year estimate) in Roanoke city, VA was 6838.00000 Persons in January of 2022, according to the United States Federal Reserve. Historically, Roanoke City, VA - Population Estimate, Total, Hispanic or Latino (5-year estimate) in Roanoke city, VA reached a record high of 6838.00000 in January of 2022 and a record low of 2527.00000 in January of 2009. Trading Economics provides the current actual value, an historical data chart and related indicators for Roanoke City, VA - Population Estimate, Total, Hispanic or Latino (5-year estimate) in Roanoke city, VA - last updated from the United States Federal Reserve on May of 2024.