Unemployment Rate in McDonald County, MO was 4.90% in February of 2024, according to the United States Federal Reserve. Historically, Unemployment Rate in McDonald County, MO reached a record high of 10.40 in July of 1992 and a record low of 1.90 in September of 2022. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in McDonald County, MO - last updated from the United States Federal Reserve on May of 2024.