Resident Population in Guadalupe County, NM was 4.29200 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Guadalupe County, NM reached a record high of 5.10000 in January of 1972 and a record low of 4.10200 in January of 1991. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Guadalupe County, NM - last updated from the United States Federal Reserve on May of 2024.